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Abstract
Nano scaffolding or nano scaffold is a medical process used to regenerate tissue and bone, including organs and organs. Nano scaffolding is a three-dimensional structure composed of very small polymer fibers. Today, nanofiber amphiphilic peptide scaffolds are good examples of this type that are used to fill bone fissures. This study was performed on 16 white and adult male rabbits weighing 2.5 3 3 kg with an age range of 1 year. The rabbits were in the same maintenance and feeding conditions. In the experimental group, the hole was filled by placing nanofiber amphiphilic scaffold scaffolds in the right tibia and in the control group, a hole with a diameter of 3 mm was left empty in the left tibia. Every two weeks, radiographs, CT scans and ultrasounds were taken from rabbits in the two groups under study. Considering the amount of F and the level of significance (P≤۰٫۰۵), it can be concluded that there is a significant difference between the control and experimental groups in the two processes. Also, due to the fact that the amount of F statistics on days 45 and 60 has increased significantly, it can be said that over time, amphiphilic nanofiber peptide scaffolds have had a positive effect on the treatment process. Considering the F level and significance level (P≤۰٫۰۵), which are all less than five percent, it can be concluded that there is a significant difference between the control and experimental groups in the healing process. Therefore, it can be said that amphiphilic nanofiber peptide scaffolds have had a positive effect on the treatment process. Evaluation of quantitative data in this study showed that nano-peptide amphiphilic scaffolds cause new bone formation as well as accelerate bone lesion regeneration. The results show that nanofiber amphiphilic peptide scaffolds have unparalleled mechanical properties, modifiable degradability rate and the ability to support the differentiation of mesenchymal stem cells to the bone category. Used a suitable scaffold for angiogenic growth factors. This process is associated with the formation of new blood vessels. Heparin is thought to bind electrostatically to the surface of peptide amphiphilic fibers, and this hybrid system stimulates the formation of blood vessels. This also increases new bone formation and the rate of bone lesion regeneration.
The method of organizing the present book is as follows.
Chapter One: Nano Scaffolding
Chapter Two: Tissue Engineering
Chapter Three: Bone Tissue
Chapter 4: Amphiphilic Peptide
Chapter 5: Bone Restoration Research
Chapter Six: Consumables and Methods
Chapter 7: Findings
Chapter 8: Summary
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